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Interestingly, DFMC collapsed rapidly after being endocytosed in tumor cells, displaying a noticeably responsive-released behavior in the presence of GSH and an acidic microenvironment (GSH = 10 mM, pH = 6.5) (Figure 4D)

PMID 8591048

If possible, its always best to test to see where your levels are first if you arent sure

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

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